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TTD Drug ID: DAP001308

Drug Information
NameTetrahydrofolic acid
Synonymsglutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-; CID91443; T3125_SIGMA; Tetrahydropteroylglutamic acid; CHEBI:20506; MolPort-001-684-176; EINECS 205-181-1; CID11442178; AC1NUT77; AC1L1ASH; (6S)-THFA; N-[4-{[(2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}benzoyl]-L-glutamic acid; AC1Q5SG4; AC1L3M37; BIT3012; (6S)-5,6,7,8-TETRAHYDROFOLATE; CHEBI:15635; CHEMBL91866; tetrahydrofolate; N-[4-({[(6S)-2-AMINO-4-OXO-1,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID; C00101; DL-Glutamic acid, N-(4-(((2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-; FH4; tetrahydropteroylglutamate; tetrahydropteroyl mono-L-glutamate; Glutamic acid, N-(p-(((2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, L-; LS-71775; folate-H4; DB00116; nchembio.108-comp12; N-(4-(((2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid; 5,6,7,8-tetrahydrofolate; 2-[[4-[(2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid; 5,6,7,8-Tetrahydropteroyl-L-glutamic acid; CHEMBL1236287; N-[4-({[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid; th-folate; (6S)-tetrahydrofolate; (2S)-2-[[4-[(2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid; 135-16-0; CID1129; 5,6,7,8-tetrahydrofolic acid; (2S)-2-[[4-[[(6S)-2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid; CID9826590; CHEBI:250731; N-(4-(((2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)glutamic acid; AR-1J1194; (6S)-Tetrahydrofolic acid; N-(5,6,7,8-tetrahydropteroyl)-L-glutamic acid; CID5460413; tetrahydrafolate; L-Glutamic acid, N-(4-(((2-amino-1,4,5,6,7,8-hexahydro-4-oxopteridinyl)methyl)amino)benzoyl)-; 29347-89-5; (6S)-5,6,7,8-tetrahydropteroylglutamate; tetrahydrofolic acid; MolPort-004-964-617; (6S)-H4folate; H4PteGlu; L-glutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-; tetra-H-folate
IndicationDietary shortage
[ICD9: 260-269   ICD10: E40-E46]
Approved    [1]
Structure

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InChI1S/C19H23N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3
-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,11-12,21,23H,5
-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t11-,12-/m0/s
1
InChIKeyMSTNYGQPCMXVAQ-RYUDHWBXSA-N
Canonical SMILESC1C(NC2=C(N1)NC(=NC2=O)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O    
Isomeric SMILESC1[C@@H](NC2=C(N1)NC(=NC2=O)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)
O
Therapeutic ClassDietary supplement
CAS NumberCAS 135-16-0
FormulaC19H23N7O6
PubChem Compound IDCID 5460413.
PubChem Substance IDSID 7890762.
ChEBI20506;
TargetFolate receptorBinder[2]
Ref 1Trimethoprim-sulfamethoxazole in the United States. Ann Intern Med. 1979 Sep;91(3):420-9. To Reference
Ref 2Common mutations at the homocysteine metabolism pathway and pediatric stroke. Thromb Res. 2001 Apr 15;102(2):115-20. To Reference



 

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