Therapeutic Targets Database
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TTD Drug ID: DAP001360

Drug Information
Nameciprofloxacin
SynonymsUNII-5E8K9I0O4U; CCRIS 5241; DivK1c_000095; Cipro I.V.; Ciprofloxacino; Cifloxin; 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinoline carboxylic acid; Fimoflox; Ciprodar; CPFX; Ciprofloxacino [INN-Spanish]; Prestwick1_000113; Cipro (TN); Proksi 500; Spectrum_000162; 17850_FLUKA; Cycin; Ciprecu; Spectrum3_001872; D00186; 3-Quinolinecarboxylic acid,1,4-dihydro-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl); AC-7613; 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid; Quinolid; SMP1_000125; KBio2_003210; Cipromycin; Ciprofloxacinum [INN-Latin]; Ciprofloxacin monohydrochloride; 1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; 33434_RIEDEL; 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID; CIPRO IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER; Ciprobay; 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-; Baflox; Cipro IV; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperzinyl)-3-quinolinecarboxylic acid HCl H2O; CHEBI:100241; 33434_FLUKA; Ciproxan; Ciproxina; BRN 3568352; AKOS000269653; Corsacin; Cipro XR; Rancif; Ciprocinol; 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid; Ciprofloxacin Hydrchloride; Proksi 250; Cyprobay; Ciproquinol; Spectrum5_001089; Liposomal-ciprofloxacin; Prestwick2_000113; Proflaxin; NCGC00095058-01; Probiox; KBio2_000642; NCGC00178128-01; Quintor; CPF; CIPRO IN DEXTROSE 5% IN PLASTIC CONTAINER; Oprea1_313572; Bacquinor; Prestwick3_000113; Flociprin; Cipro XL; Ciprofloxacin HCl; NSC620634; Bernoflox; Zumaflox; Bay o 9867; Ciprofloxacinum; Roxytal; Ciprofloxacin dihydrochloride; NCGC00016959-01; Ciloxan (*Hydrochloride*); HMS500E17; Ciprinol; C17H18FN3O3; BAY q 3939; SPBio_002065; BRD-K04804440-311-02-3; ARONIS020379; ciprofloxacin; Bay-09867; Ciprofloxacin hydrochloride; Ciflox; BSPBio_003344; MLS001336035; BAY-Q-3939; HMS2093I03; KBio3_002846; Proflox; Ciprofloxacine; BIDD:GT0205; Cixan; Prestwick0_000113; Bi-Cipro; Alcon Cilox; IDI1_000095; KBioGR_001567; Velomonit; Ipiflox; NCGC00095058-02; Ciplus; AC1L1EEW; CAS-93107-08-5; CID2764; Ciprobay Uro; Sophixin Ofteno; KBio1_000095; Ciprolin; Superocin; HMS1922E18; Septicide; SPBio_001474; Ciprofloxacin (JAN/USP/INN); KBio2_005778; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; BAS 06989041; Ciprofloxacin [USAN:INN:BAN]; Ciprolon; HSDB 6987; 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-; Cilab; Ciprofloxacine [INN-French]; Spectrum2_001567; NINDS_000095; Ciprowin; CRL-1605 & Ciprofloxacin; HMS2090O07; BSPBio_000126; Eni; 85721-33-1; Bay o 9867 (*Hydrochloride*); MolPort-000-819-654; STK021082; Baycip; Ciproxine; Spitacin; BPBio1_000140; SPECTRUM1503614; Cipro; Ciproxin; BAYQ3939; CHEMBL8; Loxan; Cipro (*Hydrochloride*); Bio-0540; Unex; Ciprofloxacina; SMR000471901; LS-141563; Citopcin; DB00537; Spectrum4_000874; Ciprogis; nchembio820-comp1; Italnik; 1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid; C05349; CBMicro_048498; Oprea1_008239; Ciriax; Ciproflox; KBioSS_000642
IndicationBacterial infections
[ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104   ICD10: A00-A09, A15-A19, A20-A28, A30-A49, A65-A69, A70-A74, A75-A79]
Approved    [1]
Structure

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InChI1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-
10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)
InChIKeyMYSWGUAQZAJSOK-UHFFFAOYSA-N
Canonical SMILESC1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O    
Therapeutic ClassAnti-Infective Agents
CAS NumberCAS 85721-33-1
FormulaC17H18FN3O3
PubChem Compound IDCID 2764.
PubChem Substance IDSID 7727.
SuperDrug ATC IDJ01MA02; S01AE03; S02AA15; S03AA07
SuperDrug CAS ID085721331;
TargetDNA topoisomerase IIInhibitor[2]
Topoisomerase IVInhibitor[2]
Ref 1How many modes of action should an antibiotic have? Curr Opin Pharmacol. 2008 Oct;8(5):564-73. Epub 2008 Jul 30. To Reference
Ref 2Isobolographic analysis of pharmacodynamic interactions between antifungal agents and ciprofloxacin against Candida albicans and Aspergillus fumigatus. Antimicrob Agents Chemother. 2008 Jun;52(6):2196-204. Epub 2008 Feb 25. To Reference



 

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