Therapeutic Targets Database
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TTD Drug ID: DAP001367

Drug Information
NameEprosartan mesylate
SynonymsEprosartan mesilate; LS-173203; 4-[[2-butyl-5-[(E)-3-hydroxy-3-oxo-2-(thiophen-2-ylmethyl)prop-1-enyl]imidazol-1-yl]methyl]benzoic acid; methanesulfonic acid; CHEMBL1200987; EPROSARTAN MESYLATE; Futuran; 144143-96-4; 2-Thiophenepropanoic acid, alpha-((2-butyl-1-((4-carboxyphenyl)methyl)-1H-imidazol-5-yl)methylene)-, (E)-, monomethanesulfonate; Eprosartan mesylate (USAN); Tevetenz; AC1NR04M; SK&F 108566-J; Navixen; SK&F-108566-J; (E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thienylimidazole-5-acrylic acid monomethanesulfonate; CHEBI:48409; (E)-2-Butyl-1-(p-carboxybenzyl)-alpha-2-thenylimidazole-5-acrylic acid, monomethanesulfonate; Teveten (TN); Eprosartan mesylate dihydrate; Eprosartan mesylate [USAN:BAN]; CID5282474; Epro-sartan mesylate dihydrate; UNII-8N2L1NX8S3; 4-({2-butyl-5-[(1E)-2-carboxy-3-(2-thienyl)prop-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid methanesulfonate; (E)-alpha-((2-butyl-1-((4-carboxyphenyl)methyl)-1H-imidazol-5-yl)methylene)-2-thiophenepropanoic acid monomethanesulfonate; Teveten; C23H24N2O4S.CH4O3S; Teveten SB; Regulaten; D02082
Trade NameTeveten
CompanyAbbott Laboratories
IndicationHigh blood pressure
[ICD9: 401   ICD10: I10, I11, I12, I13, I15]
Approved    [1]
Structure

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InChI1S/C23H24N2O4S.CH4O3S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5
-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27;1-5(2,3)4/h4-5,7-
12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H,28,29);1H3,(H,2,3,4)/b18-12+
;
InChIKeyDJSLTDBPKHORNY-XMMWENQYSA-N
Canonical SMILESCCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)C=C(CC3=CC=CS3)C(=O)O.CS(=O)(=O)O    
Isomeric SMILESCCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)/C=C(\CC3=CC=CS3)/C(=O)O.CS(=O)(=O)O
Therapeutic ClassAntihypertensive Agents
CAS NumberCAS 144143-96-4
FormulaC24H28N2O7S2
PubChem Compound IDCID 5282474.
PubChem Substance IDSID 197113.
ChEBI48409;
SuperDrug ATC IDC09CA02
C09CA02
TargetType-1 angiotensin II receptorAntagonist[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2The angiotensin receptor blocker eprosartan mesylate reduces pulse pressure in isolated systolic hypertension. Can J Cardiol. 2004 Oct;20 Suppl C:11C-16C. To Reference



 

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