TTD Drug ID: DAP001387

Drug Information
Name	Gatifloxacin
Synonyms	Kinome_3137; MLS000040259; (+-)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; Gatifloxacin; SAM002589955; PD-135432; 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; MLS000759493; Spectrum3_000999; BMS-206584; AM 1155; Gatiflo; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; Gatifloxacin (TN); 160738-57-8; AM-1155; S1340_Sellekc; KBio3_001917; D08011; Spectrum2_000487; NCGC00095126-02; 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; S1340_Selleck; Zymer (TN); TL8001438; BMS-206584-01; PD135432; CPD000043336; KBio2_005010; AC1L1K82; Tequin in dextrose 5% in plastic container; FT-0082686; Zymar; Spectrum4_001127; KBioSS_002448; GTFX; HMS2093G06; Gatispan; Gatilox; AC-1944; AKOS004119932; SPBio_000353; Gatifloxacin (INN); CID5379; LS-184402; Gatiquin; CHEBI:5280; BRD-A74980173-001-02-8; Zymaxid; KBio2_007578; 180200-66-2; Tequin; SMR000043336; 112811-59-3; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-; AM-1155 (*Sesquihydrate*); Zymer; CG-5501; Gatifloxacin & Gamma Interferon; I06-2286; KBioGR_001613; Gatifloxacin [USAN:INN]; 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; MolPort-001-738-626; Spectrum_001909; NCGC00178525-01; HMS2090K10; I06-2287; C07661; KBio2_002442; BSPBio_002697; Spectrum5_001468; HMS1922J15; NCGC00095126-01; CHEMBL31; CG 5501; PD 135432; STK801620; SAM001246715; Gatiflo,Tequin and Zymar, Gatifloxacin; BMS 206584-01; BB_SC-1123; DB01044; SPECTRUM1504272; Gaity; Bonoq
Trade Name	Gatiflo; Tequin; Zymar
Company	Bristol-Myers Squibb
Indication	Respiratory tract infections [ICD9: 460-519   ICD10: J00-J99]			Approved    [1]
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)2 3(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,2 5,26)
InChIKey	XUBOMFCQGDBHNK-UHFFFAOYSA-N
Canonical SMILES	CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
Therapeutic Class	Anti-Infective Agents
CAS Number	CAS 112811-59-3
Formula	C19H22FN3O4
PubChem Compound ID	CID 5379.
PubChem Substance ID	SID 9863.
SuperDrug ATC ID	J01MA16; S01AE06
SuperDrug CAS ID	112811593;
Target	DNA topoisomerase II			Inhibitor	[2]
	Topoisomerase IV			Inhibitor	[2]
Ref 1	Novel agents in the management of Mycobacterium tuberculosis disease. Curr Med Chem. 2007;14(18):2000-8. To Reference
Ref 2	Antimicrob Agents Chemother. 1998 Oct;42(10):2678-81.Inhibitory activities of gatifloxacin (AM-1155), a newly developed fluoroquinolone, against bacterial and mammalian type II topoisomerases. To Reference

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