Therapeutic Targets Database
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TTD Drug ID: DAP001399

Drug Information
NameMepyramine
SynonymsHarvamine; NCGC00015822-02; Neo-Bridal; 2-((2-(Dimethylamino)ethyl)-(p-methoxybenzyl)amino)pyridine; Coradon; nchembio714-comp2; KBioSS_001384; [3H]mepyramine; KBio2_006520; D08183; 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-; DivK1c_000175; IDI1_000175; Nyscaps; [3H]pyrilamine; 102206-59-7; Tocris-0660; Mepiramina; Stamine; Dorantamin; Mepyraminum; AKOS001637059; NCGC00015822-01; Pyranisamine; N-Dimethylamino-aethyl-N-p-methoxy-benzyl-.alpha.-amino-pyridin-maleat; NCGC00023513-04; KBio1_000175; N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine; N-para-Methoxybenzyl-N',N'-dimethyl-N-alpha-pyridylethylenediamine; p-Methoxybenzyl-alpha-pyridyl-dimethyl-aethylendiamin [German]; Histasan; Pyramal; Mepyramine; 2-((p-Methoxybenzyl)(2-(dimethylamino)ethyl)amino)pyridine; Statomin; Isamin; BSPBio_000198; Pyridine, 2-[[2-(dimethylamino)ethyl][p-methoxybenzyl)amino]]-; N-((4-Methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine; NCGC00015822-03; Parmal; KBio2_003952; 2-[(p-Methoxybenzyl)[2-(dimethylamino)ethyl]amino]pyridine; Antalergan; KBio2_001384; Mepiramina [INN-Spanish]; CCRIS 4865; N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine; N',N'-Dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine; Mepyramine (INN); BRN 0269019; Stangen; Pyridine, 2-[(p-methoxybenzyl)[2-(dimethylamino)ethyl]amino]-; CAS-59-33-6; Afko-Hist; Pyridine, 2-((p-methoxybenzyl)(2-(dimethylamino)ethyl)amino)-; BIDD:GT0215; Prestwick1_000289; Prestwick0_000289; AC1L1JDF; 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine; Anhistol; N-(p-Methoxybenzyl)-N',N'-dimethyl-N-(.alpha.-pyridyl)ethylenediamine; Lopac-P-5514; Mepyren; NSC 13136; BRD-K97564742-050-05-3; NCGC00015822-10; Antamine; Anhistabs; 5-22-08-00381 (Beilstein Handbook Reference); N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridyl-1,2-ethanediamine; Thylogen; N-(para-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridylethylenediamine; Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]-; NCGC00023513-02; p-Methoxy-benzyl-.alpha.-pyridyl-dimethyl-aethylendiamin; N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-(pyridylethylene)diamine; Ethylenediamine, N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)-; Copsamine; Prestwick2_000289; N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridylethylenediamine; MolPort-001-794-651; L000391; 91-84-9; Paraminyl; ST50443109; R.d. 2786; Spectrum2_001306; Pyrilamide; EINECS 202-102-2; N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine; Mepyramin; CHEMBL511; N,N-dimethyl-N'-{[4-(methyloxy)phenyl]methyl}-N'-pyridin-2-ylethane-1,2-diamine; N-p-Methoxybenzyl-N',N'-dimethyl-N-alpha-pyridylethylenediamine; Lopac0_000890; NCI-C60651; HSDB 5187; Spectrum_000904; Spectrum3_000605; NCGC00023513-05; Histapyran; Mepiramine; 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-; 2-[[2-(Dimethylamino)ethyl]-(p-methoxybenzyl)amino]pyridine; Dipane; BSPBio_002110; Mepyramin [German]; WLN: T6NJ BN2N1&1&1R DO1; CID4992; KBio3_001610; Maranhist; AC1Q4CO6; C11798; NINDS_000175; SPBio_002417; Antallergan; Spectrum4_000493; 2-dimethylaminoethyl-p-anisyl-(2-pyridyl)amine; PYRA; Anthisan; Spectrum5_001264; Wait's green mountain antihistamine; Histalon; UNII-HPE317O9TL; Mepyraminum [INN-Latin]; NCGC00023513-06; Oprea1_317349; Pyridine, 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-; LS-1930; Histacap; KBioGR_001005; pyrilamine; Pyrilamine salt with fine resin; HMS2089M19; BRD-K97564742-050-04-6; WLN: T6NJ DN1R DO1&2N1&1; BPBio1_000218; SPBio_001371; Kriptin; Neobridal; NSC13136; RP 2786; N-(p-Methoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine; Mepyramine [INN:BAN]; p-Methoxybenzyl-alpha-pyridyl-dimethyl-aethylendiamin; Neoantergan; AB00053539; CHEBI:6762; Prestwick3_000289; N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine
IndicationAllergies
[ICD9: 995.3   ICD10: T78.4]
Approved    [1]
Structure

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InChI1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3
)10-8-15/h4-11H,12-14H2,1-3H3
InChIKeyYECBIJXISLIIDS-UHFFFAOYSA-N
Canonical SMILESCN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2    
Therapeutic ClassAnti-Asthmatic Agents
CAS NumberCAS 91-84-9
FormulaC17H23N3O
PubChem Compound IDCID 4992.
PubChem Substance IDSID 13962.
ChEBI6762;
SuperDrug ATC IDD04AA02; R06AC01
SuperDrug CAS ID000091849;
TargetHistamine H1 receptorAntagonist[1][2][3]
Ref 1Antinociception induced by central administration of histamine in the formalin test in rats. Indian J Physiol Pharmacol. 2008 Jul-Sep;52(3):249-54. To Reference
Ref 2Receptor mediation and nociceptin inhibition of bradykinin-induced plasma extravasation in the knee joint of the rat. Inflamm Res. 2009 Jun 21. [Epub ahead of print] To Reference
Ref 3Design, synthesis and histamine H1-receptor antagonistic activity of some novel 4-amino-2-(substituted)-5-(substituted) aryl-6-[(substituted aryl) amino] pyrimidines. Arzneimittelforschung. 2009;59(5):243-7. To Reference



 

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