Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DAP001403

Drug Information
NameMizolastine
SynonymsC24H25FN6O; Mizollen; CID65906; AC-634; Schwarz brand of mizolastine; 108612-45-9; Zolistam; Mistalin; UNII-244O1F90NA; CHEBI:252819; MolPort-002-885-879; ST51052747; Mizolastinum; CCRIS 8410; Mizolastine [INN]; SL 85.0324; Novag brand of mizolastine; Mizolastinum [INN-Latin]; Sanofi Synthelabo brand of mizolastine; ZINC13831810; Mizollen (TN); MKC-431; NCGC00181013-01; I06-0373; CHEMBL94454; 2-((1-(1-(p-Fluorobenzyl)-2-benzimidazolyl)-4-piperidyl)methylamino)-4(3H)-pyrimidinone; LS-135935; AC1L247Z; Zolim; SL-85.0324; Mizolastine (JAN/INN); C076170; Zolistan; AKOS005145756; Allphar brand of mizolastine; Mizolastina; Mizolastine; Mistamine; Mizolastina [INN-Spanish]; 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluorophenyl)methyl)-1H-benzimidazol-2-yl)-4-piperidinyl)methylamino)-; Mizolen; Galderma brand of mizolastine; D01117; 2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one
Trade NameMizollen
IndicationAllergic rhinitis
[ICD9: 477   ICD10: J30]
Approved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)
24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,
11-12,14-16H2,1H3,(H,26,28,32)
InChIKeyPVLJETXTTWAYEW-UHFFFAOYSA-N
Canonical SMILESCN(C1CCN(CC1)C2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F)C5=NC=CC(=O)N5    
Therapeutic ClassAnti-Allergic Agents
CAS NumberCAS 108612-45-9
FormulaC24H25FN6O
PubChem Compound IDCID 65906.
PubChem Substance IDSID 207953.
SuperDrug ATC IDR06AX25
SuperDrug CAS ID108612459;
TargetHistamine H1 receptorAntagonist[2]
Ref 1Population pharmacokinetic analysis and optimization of the experimental design for mizolastine solution in children. J Pharmacokinet Pharmacodyn. 2001 Jun;28(3):299-319. To Reference
Ref 2Histamine H1-receptor antagonists inhibit nuclear factor-kappaB and activator protein-1 activities via H1-receptor-dependent and -independent mechanisms. Clin Exp Allergy. 2008 Jun;38(6):947-56. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543