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TTD Drug ID: DAP001412

Drug Information
NameOlmesartan medoxomil
SynonymsKBio3_002711; Olmesartan medoxomil (JAN/USAN); KBio2_007626; Cs 866; NCGC00095136-01; MolPort-005-935-047; LS-181818; AC1L2Y71; HMS1922L15; (5-methyl-2-oxo-1,3-dioxolen-4-yl)methoxy-4-(1-hydroxy-1-methylethyl)-2-propyl-1-(4-(2-(tetrazol-5-yl)phenyl)phenyl)methylimidazol-5-carboxylate; Olmesartan medoxomil; 1H-imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester; DE-092; BRD-K78485176-001-02-9; KS-1182; Olmesartan medoximil; CHEMBL1200692; Benicar (TN); Spectrum2_000506; DB00275; CS-866RN; CS-866; D01204; NCGC00095136-02; Sankyo Brand of Olmesartan Medoxomil; L001061; MolPort-003-666-605; KBio2_005058; BSPBio_003491; 144689-63-4; KBioSS_002498; Olvance; 1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester; SPBio_000431; Olmetec; KBioGR_001040; Forest Brand of Olmesartan Medoxomil; Spectrum3_001676; (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate; HMS2089K18; Berlin-Chemie Brand of Olmesartan Medoxomil; CID130881; SPECTRUM1505205; S1587_Selleck; UNII-6M97XTV3HD; I06-0025; Benevas; Spectrum_001944; Spectrum5_001556; Bio-0071; Spectrum4_000740; KBio2_002490; C097933; CS-866DM; Olmetec (TN); Benicar, Olmetec,Olmesartan; AC-1601; HMS2093K16; Benicar; 1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-, (5-methyl-2-oxo-1,3-dioxol-4-yl) methyl ester
IndicationHigh blood pressure
[ICD9: 401   ICD10: I10, I11, I12, I13, I15]
Approved    [1]
Structure

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InChI1S/C29H30N6O6/c1-5-8-23-30-25(29(3,4)38)24(27(36)39-16-22-17(2)40
-28(37)41-22)35(23)15-18-11-13-19(14-12-18)20-9-6-7-10-21(20)26-3
1-33-34-32-26/h6-7,9-14,38H,5,8,15-16H2,1-4H3,(H,31,32,33,34)
InChIKeyUQGKUQLKSCSZGY-UHFFFAOYSA-N
Canonical SMILESCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)OCC5=C(OC(=O)O5)C)
C(C)(C)O    
Therapeutic ClassAntihypertensive Agents
CAS NumberCAS 144689-63-4
FormulaC29H30N6O6
PubChem Compound IDCID 130881.
PubChem Substance IDSID 707351.
SuperDrug ATC IDC09CA08
SuperDrug CAS ID144689634;
TargetType-1 angiotensin II receptorAntagonist[2]
Ref 1Effect of angiotensin receptor blockade on endothelial function: focus on olmesartan medoxomil. Vasc Health Risk Manag. 2009;5(1):301-14. Epub 2009 Apr 8. To Reference
Ref 2Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers. J Cardiovasc Pharmacol. 2009 Jul;54(1):47-56. To Reference



 

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