Therapeutic Targets Database
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TTD Drug ID: DAP001431

Drug Information
NameTetracaine
Synonyms4-14-00-01172 (Beilstein Handbook Reference); Tetracainum; AC-3480; Pontocaine; Diaethylaminoaethanol ester der p-butylaminobenzoesaeure; 4-[Butylamino]benzoic acid-2-[dimethylamino]ethyl ester; NCGC00016049-02; NINDS_000607; tetracaine; 2-dimethylaminoethyl 4-(butylamino)benzoate; Uromucaesthin; 136-47-0 (mono-hydrochloride); CAS-136-47-0; 2-(Dimethylamino)ethyl 4-(butylamino)benzoate; Prestwick0_000571; Tetracaina; SPBio_002601; Dicaine; Prestwick1_000571; KBio2_001512; NCGC00162367-01; Spectrum_001032; BRD-K45071273-003-05-8; Dicain; Spectrum2_001328; T7383_SIAL; KBio3_001444; KBio2_006648; NCGC00016049-04; Prestwick3_000571; BSPBio_001944; Mucaesthin; Tetracaina [INN-Spanish]; Spectrum5_001072; Spectrum4_000351; Prestwick2_000571; Laudocaine; D00551; Medihaler-Tetracaine; Dikain; Lopac0_001211; I01-1872; BSPBio_000382; KBioSS_001512; CHEBI:9468; SPBio_001455; NCGC00016049-01; C15H24N2O2; C07526; Fissucain; SBB058194; T3812_SIAL; 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester; BENZOIC ACID,4-BUTYLAMINO,2-DIMETHYLAMINOETHYL ESTER PANTOCAIN BASE; Lopac-T-7508; InChI=1/C15H24N2O2/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3/h6-9,16H,4-5,10-12H2,1-3H; EINECS 202-316-6; Amethocaine; AC1L1KAQ; Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester; Dimethylaminoethyl p-butyl-aminobenzoate; MolPort-001-783-476; 2-(Dimethylamino)ethyl p-(butylamino)benzoate; Contralgin; Tetrakain [Czech]; Tetrakain; LS-36312; DivK1c_000607; Meethobalm; Tetracaine (USP/INN); AB00053549; Anetain; Metraspray; Rexocaine; Medicaine; p-Butylaminobenzoyl-2-dimethylaminoethanol; UNII-0619F35CGV; Tetracainum [INN-Latin]; Tetracaine [USAN:INN]; CHEMBL698; T7383_SIGMA; BENZOIC ACID, p-(BUTYLAMINO)-, 2-(DIMETHYLAMINO)ETHYL ESTER; KBioGR_000781; CID5411; Niphanoid; 2-Dimethylaminoethylester kyseliny p-butylaminobenzoove; p-(Butylamino)benzoic acid, 2-(dimethylamino)ethyl ester; KBio2_004080; IDI1_000607; KBio1_000607; 2-Dimethylaminoethylester kyseliny p-butylaminobenzoove [Czech]; BPBio1_000422; Spectrum3_000562; Diaethylaminoaethanol ester der p-butylaminobenzoesaeure [German]; Amethocaine (TN); 94-24-6; Intercain; BRN 2216051
Trade NamePontocaine
IndicationSpinal anesthesia
[ICD9: 338   ICD10: R52]
Approved    [1]
Structure

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InChI1S/C15H24N2O2/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3
/h6-9,16H,4-5,10-12H2,1-3H3
InChIKeyGKCBAIGFKIBETG-UHFFFAOYSA-N
Canonical SMILESCCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C    
Therapeutic ClassAnesthetics
CAS NumberCAS 94-24-6
FormulaC15H24N2O2
PubChem Compound IDCID 5411.
PubChem Substance IDSID 9729.
SuperDrug ATC IDC05AD02; D04AB06; N01BA03; S01HA03
SuperDrug CAS ID000094246;
TargetVoltage-gated sodium channel subunit alpha Nav1.8Inhibitor[2]
Ref 1Evaluation of a novel topical anesthetic agent for cutaneous laser resurfacing: a randomized comparison study. Dermatol Surg. 2002 Nov;28(11):1004-6; discussion 1006. To Reference
Ref 2Heterologous expression and functional analysis of rat Nav1.8 (SNS) voltage-gated sodium channels in the dorsal root ganglion neuroblastoma cell line ND7-23. Neuropharmacology. 2004 Mar;46(3):425-38. To Reference



 

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