Therapeutic Targets Database
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TTD Drug ID: DAP001445

Drug Information
NameLasofoxifene
SynonymsC3D; (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol; Lasofoxifene; CP 336156; CP-336,156; 2-Naphthalenol, 5,6,7,8-tetrahydro-6-phenyl-5-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-, (5R-cis)-; LS-192130; CID216416; MolPort-006-394-766; cis-1R-(4'-pyrrolidinoethoxyphenyl)-2S-phenyl-6-hydroxy-1,2,3,4-tetrahydronaphthalene, tartrate salt; CHEBI:41282; UNII-337G83N988; AC1L50OI; CHEMBL328190; Lasofoxifene [INN]; 180916-16-9; Oporia; 2-Naphthalenol, 5,6,7,8-tetrahydro-6-phenyl-5-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-, (5R,6S)-
CompanyPfizer
IndicationOsteoporosis
[ICD9: 733.0   ICD10: M80-M81]
Approved    [1]
Structure

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InChI1S/C28H31NO2/c30-24-11-15-27-23(20-24)10-14-26(21-6-2-1-3-7-21)28
(27)22-8-12-25(13-9-22)31-19-18-29-16-4-5-17-29/h1-3,6-9,11-13,15
,20,26,28,30H,4-5,10,14,16-19H2/t26-,28+/m1/s1
InChIKeyGXESHMAMLJKROZ-IAPPQJPRSA-N
Canonical SMILESC1CCN(C1)CCOC2=CC=C(C=C2)C3C(CCC4=C3C=CC(=C4)O)C5=CC=CC=C5    
Isomeric SMILESC1CCN(C1)CCOC2=CC=C(C=C2)[C@H]3[C@H](CCC4=C3C=CC(=C4)O)C5=CC=CC=C5
CAS NumberCAS 180916-16-9
FormulaC28H31NO2
PubChem Compound IDCID 216416.
PubChem Substance IDSID 789595.
SuperDrug ATC IDG03XC03
TargetEstrogen receptorModulator[1]
Ref 1Pfizer. Product Development Pipeline. March 31 2009. To Reference



 

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