TTD Drug ID: DAP100399

Drug Information
Name	Doxycycline
Synonyms	Vibramycin Novum; Spectrum2_000143; DivK1c_000345; CHEBI:50845; NSC633557; Doxycycline (INN); 6-Deoxyoxytetracycline; Doxycyclin; AC1O8PYM; alpha-Doxycycline; 94088-85-4 (calcium salt (1:2)); 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)-; 7264-10-0; DOXYCYCLINE MONOHYDRATE; Hydramycin; Doxitard; Doxycyclinum; KBioGR_001133; SMP1_000107; Lopac0_000405; doxycycline; LS-187766; Supracyclin; BCBcMAP01_000024; AC1NQXW7; CID5463943; Doxivetin; Doxycycline (200mg/day) or Placebo; SPBio_002784; Doxycycline hyclate; Monodox; Spectrum5_000947; Doxiciclina; KBio2_003855; Apo-Doxy; 24390-14-5; HMS2090E06; BSPBio_001936; Vibramycin; Doxy-Puren; Doxytec; DB00254; Prestwick3_000852; Liviatin; Prestwick2_000852; NCGC00179395-01; CID5281011; DOXCYCLINE ANHYDROUS; Doxytetracycline; (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; Doxycycline (anhydrous); 6-Deoxytetracycline; 6alpha-Deoxy-5-oxytetracycline; Azudoxat; Vibravenos; DOXYCYCLINE CALCIUM; BMY-28689; NINDS_000345; Prestwick0_000852; Doxychel (TN); 69935-17-7 (mono-hydrochloride, di-hydrate); NCGC00161602-01; Doxiciclina [INN-Spanish]; (2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; Vivox (*Hyclate); EINECS 209-271-1; KBio1_000345; LS-93868; 564-25-0; 7164-70-7; DMSC (*Fosfatex); Spectrum_000807; KBio2_001287; HSDB 3071; Oracea; Doxychel; 6-alpha-Deoxy-5-oxytetracycline; Doxycycline anhydrous; (2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; Doxysol; CID6713981; Jenacyclin; UPCMLD-DP021:001; BIDD:GT0146; Novo-Doxylin; C06973; Doxy-Caps; Deoxymykoin; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS); Doxycen; Ronaxan; STOCK1N-34341; alpha-6-Deoxyoxytetracycline; BU-3839T; 5-Hydroxy-alpha-6-deoxytetracycline; Alti-Doxycycline; Doxycycline (internal use); Vibra-tabs; NCGC00167961-01; 10597-92-9; NCGC00161602-03; CID5353597; IDI1_000345; GS-3065 (*monohydrate); KBio2_006423; BSPBio_000863; alpha-6-Deoxy-5-hydroxytetracycline; Doxycyclinum [INN-Latin]; Spectrum3_000408; Dossiciclina [DCIT]; BPBio1_000951; Doxycin; Doxiciclina [Italian]; Vibramycine; KBioSS_001287; Doxycycline-Chinoin; 2-Naphthacenecarboxamide, 4-alpha-S-(dimethylamino)-1,4,4a-alpha-5,5a-alpha,6,11,12a-octahydro-3,5-alpha,10,12,12a-alpha-pentahydroxy-6-alpha-methyl-1,11-dioxo-; SPBio_000246; Vibramycin (*monohydrate); AB08 (*Fosfatex); Dossiciclina; KBio3_001156; CHEMBL1433; Investin; Oxytetracycline, 6-deoxy-; UPCMLD-DP021; MolPort-002-507-423; D07876; Doxycycline (TN); Prestwick1_000852; 41411-66-9 (6-epimer, mono-hydrochloride); Atridox; AC1NS4CW; Doxy-Tabs; AC1NUYS8; CPD001550033; DOXY; UNII-334895S862; NCGC00161602-04; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha))-; (2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; Monodox (*monohydrate); (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 17086-28-1 (mono-hydrate); Spectrum4_000527; Spanor; SAM002589932; Nu-Doxycycline
Trade Name	Periostat
Company	Collagenex
Indication	Advanced gum disease, chronic periodontitis [ICD9: 523.4, 523.5   ICD10: K05.3, K05.4]			Approved    [1]
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
Therapeutic Class	Antiinflammatory
CAS Number	CAS 564-25-0
Formula	C22H24N2O8
PubChem Compound ID	CID 5281011.
PubChem Substance ID	SID 9187.
ChEBI	50845;
SuperDrug ATC ID	A01AB22; J01AA02
SuperDrug CAS ID	000564250;
Target	MMP-8			Inhibitor	[2][3][4]
Ref 1	How many modes of action should an antibiotic have? Curr Opin Pharmacol. 2008 Oct;8(5):564-73. Epub 2008 Jul 30. To Reference
Ref 2	16498445
Ref 3	17199549
Ref 4	20370419

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