Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000038

Drug Information
CompanyAuris Medical
IndicationHearing Loss
[ICD9: 389   ICD10: H90-H91]
Phase I/II completed    
TargetStress-activated protein kinase JNK1Inhibitor[1][2]
Ref 1AM-111 reduces hearing loss in a guinea pig model of acute labyrinthitis. Laryngoscope. 2007 Dec;117(12):2174-82. To Reference
Ref 2Intratympanic treatment of acute acoustic trauma with a cell-permeable JNK ligand: a prospective randomized phase I/II study. Acta Otolaryngol. 2007 Sep;127(9):938-42. To Reference


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