Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000101

Drug Information
SynonymsAKOS005145763; 2-(3-(4-Ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol; Dapagliflozin (INN/USAN); Dapagliflozin; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-; D08897; BMS-512148; CID9887712; BMS-512148, Dapagliflozin; 461432-26-8; D-Glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-ethoxyphenyl)methyl)phenyl)-, (1S)-; BMS 512148; CHEMBL429910; S1548_Selleck
IndicationDiabetes Mellitus Type 2
[ICD9: 250   ICD10: E11]
Phase III    

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Canonical SMILESCCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl    
Isomeric SMILESCCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)
CAS NumberCAS 461432-26-8
PubChem Compound IDCID 9887712.
PubChem Substance IDSID 14855234.
SuperDrug ATC IDA10BX09
TargetSodium/glucose cotransporter 2Blocker[1][2][3]
Ref 1Dapagliflozin for the treatment of type 2 diabetes. Ann Pharmacother. 2009 Jul;43(7):1286-93. Epub 2009 Jul 7. To Reference
Ref 2A Study of Dapagliflozin in Patients With Type 2 Diabetes on High Doses of Insulin Plus Insulin Sensitizers: Applicability of a Novel Insulin-Independent Treatment. Diabetes Care. 2009 Jun 15. [Epub ahead of print] To Reference
Ref 3Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2009 Mar;31(2):107-46. To Reference


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