Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000103

Drug Information
Synonyms(4R)-4-[(3,4-dichlorobenzoyl)amino]-5-[3-methoxypropyl(pentyl)amino]-5-oxopentanoic acid; 119817-90-2; AC1L24A8; Dexloxiglumida [INN-Spanish]; Dexloxiglumidum [INN-Latin]; Dexloxiglumide; CHEMBL550781; CID65937; Dexloxiglumidum; CR-2017; AKOS000279054; Dexloxiglumida; AC1Q3MXI; C103490; n2-(3,4-dichlorobenzoyl)-n1-(3-methoxypropyl)-n1-pentyl-d-a-glutamine
IndicationIrritable Bowel Syndrome, Gastroesophageal Reflux Disease
[ICD9: 530, 564.1   ICD10: K21, K58]
Phase III completed, and Positive results in phase III    [1]

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Canonical SMILESCCCCCN(CCCOC)C(=O)C(CCC(=O)O)NC(=O)C1=CC(=C(C=C1)Cl)Cl    
CAS NumberCAS 119817-90-2
PubChem Compound IDCID 65937.
PubChem Substance IDSID 207988.
TargetCholecystokinin receptor type AAntagonist[2][3][4]
Ref 1Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313. To Reference
Ref 2Prokinetic drugs for feed intolerance in critical illness: current and potential therapies. Crit Care Resusc. 2009 Jun;11(2):132-43. To Reference
Ref 3Regulation of fat-stimulated neurotensin secretion in healthy subjects. J Clin Endocrinol Metab. 2008 May;93(5):1964-70. Epub 2008 Feb 26. To Reference
Ref 4Role of CCK and potential utility of CCK1 receptor antagonism in the treatment of pancreatitis induced by biliary tract obstruction. Br J Pharmacol. 2008 Apr;153(8):1650-8. Epub 2008 Feb 25. To Reference


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