Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DCL000120

Drug Information
NameGMX1777
CompanyGemin X
IndicationLymphoma, Solid Tumors
[ICD9: 140-199, 202.8, 210-229   ICD10: C00-C75, C7A, C7B, C81-C96, D10-D36, D3A]
Phase I    
Structure

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InChI1S/C30H42ClN5O8.ClH/c1-38-16-17-39-18-19-40-20-21-41-22-23-43-30(
37)44-25-36-13-10-27(11-14-36)35-29(34-24-32)33-12-4-2-3-5-15-42-
28-8-6-26(31)7-9-28;/h6-11,13-14H,2-5,12,15-23,25H2,1H3,(H,33,34)
;1H
InChIKeyDAHMXVAETAAQOZ-UHFFFAOYSA-N
Canonical SMILESCOCCOCCOCCOCCOC(=O)OC[N+]1=CC=C(C=C1)NC(=NCCCCCCOC2=CC=C(C=C2)Cl)NC#N.
[Cl-]    
Therapeutic ClassAntineoplastic Agents
PubChem Compound IDCID 9961434.
ClinicalTrials.govNCT00457574;
TargetNuclear factor NF-kappa-BInhibitor[1]
Ref 1Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777. Anticancer Drugs. 2009 Jun;20(5):346-54. To Reference



 

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