Therapeutic Targets Database
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TTD Drug ID: DCL000149

Drug Information
NameLintitript
SynonymsUNII-3YFV00531K; PDSP2_000932; SR-27897B; AC1L3TXG; PDSP1_000946; CHEMBL249973; C20H14ClN3O3S; SR 27897B; 1-((2-(4-(2-Chlorophenyl)thiazol-2-yl)aminocarbonyl)indolyl)acetic acid; LS-172957; NCGC00167729-01; 136381-85-6; SR-27897; SR 27897; 2-((4-(o-Chlorophenyl)-2-thiazolyl)carbamoyl)indole-1-acetic acid; SR27897; CID122077; 1H-Indole-1-acetic acid, 2-(((4-(2-chlorophenyl)-2-thiazolyl)amino)carbonyl)-; 2-[2-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]indol-1-yl]acetic acid; L000575; BRD-K35629949-001-01-2; Lintitript
CompanySanofi-aventis
IndicationPancreatic Cancer, Obesity
[ICD9: 140-229, 157, 278   ICD10: C00-C96, C25, E66]
Discontinued    
Structure

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InChI1S/C20H14ClN3O3S/c21-14-7-3-2-6-13(14)15-11-28-20(22-15)23-19(27)
17-9-12-5-1-4-8-16(12)24(17)10-18(25)26/h1-9,11H,10H2,(H,25,26)(H
,22,23,27)
InChIKeyILNRQFBVVQUOLP-UHFFFAOYSA-N
Canonical SMILESC1=CC=C2C(=C1)C=C(N2CC(=O)O)C(=O)NC3=NC(=CS3)C4=CC=CC=C4Cl    
Therapeutic ClassAntineoplastic Agents
CAS NumberCAS 136381-85-6
PubChem Compound IDCID 122077.
PubChem Substance IDSID 698591.
TargetCholecystokinin type A (CCK-A) receptorAntagonist[1][2]
Ref 1A cholecystokinin-1 receptor agonist (CCK-8) mediates increased permeability of brain barriers to leptin. Br J Pharmacol. 2008 Jul;154(5):1009-15. Epub 2008 Apr 21. To Reference
Ref 2A novel role for cholecystokinin: regulation of mesenteric vascular resistance. Regul Pept. 2004 Sep 15;121(1-3):145-53. To Reference



 

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