Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000170

Drug Information
CompanyTakeda & Millennium
IndicationAcute myelogenous leukemia, High-risk myelodysplastic syndrome and Ovarian cancer
[ICD9: 140-229, 183, 205.0, 208.9, 238.7   ICD10: C00-C96, C56, C91-C95, C92.0, D46]
Phase II    
Advanced solid tumours and haematological malignancies
[ICD9: 140-229   ICD10: C00-C96]
Phase I    
Paediatric solid tumours or ALL
[ICD9: 140-199   ICD10: C00-C75, C7A, C7B]
Phase I/II    

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Canonical SMILESCOC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)
Therapeutic ClassAntineoplastic Agents
PubChem Compound IDCID 24771867.
TargetAurora A kinaseInhibitor[1]
Ref 1Effect of Aurora A kinase inhibitor MLN8237 combined with rituximab on antitumor activity in preclinical B-cell non-Hodgkin's lymphoma models. Journal of Clinical Oncology, 2009:8553 To Reference


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