TTD Drug ID: DCL000193

Drug Information
Name	Pasireotide
Company	Novartis
Indication	Neuroendocrine Tumor; Carcinoid Tumor; Pancreatic Neuroendocrine Tumor [ICD9: 140-199, 157.4, 209, 209.4, 209.5, 209.6, 210-229   ICD10: C00-C75, C25.4, C75, C7A, C7B, D10-D36, D3A, E34.0]			Phase I    [1]
	Pancreatic Cancer			Phase III    [1]
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C58H66N10O9/c59-27-13-12-22-46-52(69)64-47(30-38-23-25-42(26-2 4-38)76-36-39-16-6-2-7-17-39)53(70)66-49(31-37-14-4-1-5-15-37)57( 74)68-35-43(77-58(75)61-29-28-60)33-50(68)55(72)67-51(40-18-8-3-9 -19-40)56(73)65-48(54(71)63-46)32-41-34-62-45-21-11-10-20-44(41)4 5/h1-11,14-21,23-26,34,43,46-51,62H,12-13,22,27-33,35-36,59-60H2, (H,61,75)(H,63,71)(H,64,69)(H,65,73)(H,66,70)(H,67,72)/t43-,46+,4 7+,48-,49+,50+,51?/m0/s1
InChIKey	VMZMNAABQBOLAK-CIXMYWCRSA-N
Canonical SMILES	C1C(CN2C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C2=O)CC3=CC=CC=C3)CC4= CC=C(C=C4)OCC5=CC=CC=C5)CCCCN)CC6=CNC7=CC=CC=C76)C8=CC=CC=C8)OC(=O)NCCN
Isomeric SMILES	C1[C@@H](CN2[C@H]1C(=O)NC(C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N [C@@H](C2=O)CC3=CC=CC=C3)CC4=CC=C(C=C4)OCC5=CC=CC=C5)CCCCN)CC6=CNC7=CC= CC=C76)C8=CC=CC=C8)OC(=O)NCCN
CAS Number	CAS 396091-73-9
PubChem Compound ID	CID 71300636.
SuperDrug ATC ID	H01CB05
	H01CB05
ClinicalTrials.gov	NCT00804336;
	NCT00994110;
Target	Somatostatin receptor type 1			Agonist	[1]
	Somatostatin receptor type 1			Multitarget	[1]
	Somatostatin receptor type 2			Agonist	[1]
	Somatostatin receptor type 2			Multitarget	[1]
	Somatostatin receptor type 3			Agonist	[1]
	Somatostatin receptor type 3			Multitarget	[1]
	Somatostatin receptor type 5			Agonist	[1]
	Somatostatin receptor type 5			Multitarget	[1]
Ref 1	Treatment strategies for acromegaly. Expert Opin Emerg Drugs. 2005 Nov;10(4):875-90. To Reference

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