Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000194

Drug Information
SynonymsCHEMBL372764; C105905; FT-0083490; ST51054138; (1,1-dimethylpiperidin-1-ium-4-yl) octadecyl phosphate; KRX-0401, NSC 639966; Perifosine; octadecyl-(1,1-dimethyl-4-piperidylio)phosphate; Piperidinium, 4-((hydroxy(octadecyloxy)phosphinyl)oxy)-1,1-dimethyl-, inner salt; CID148177; UNII-2GWV496552; AKOS005146344; I14-1991; NSC 639966; KRX-0401; D-21266; NKA17; Piperidinium, 4-[[hydroxy(octadecyloxy)phosphinyl]oxy]-1,1-dimethyl-, inner salt; NSC-639966; 4-((Hydroxy(octadecyloxy)phosphinyl)oxy)-1,1-dimethylpiperidinium inner salt; D 21266; S1037_Selleck; AC1L3WLE; 157716-52-4; MolPort-005-943-222
CompanyAEterna Zentaris
IndicationNon-small Cell Lung CancerTerminated in Phase II    
Refractory Multiple Myeloma, Recurrent Malignant Glioma, Rare Sarcoma's Refractory
[ICD9: 191, 203.0   ICD10: C71, C90.0]
Phase II    

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Therapeutic ClassAntineoplastic Agents
PubChem Compound IDCID 148177.
PubChem Substance IDSID 499931.
TargetProtein kinase BInhibitor[1][2][3]
Ref 1Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling. PLoS Biol. 2009 Jun 2;7(6):e1000121. Epub 2009 Jun 2. To Reference
Ref 2Emerging treatments for multiple myeloma: beyond immunomodulatory drugs and bortezomib. Semin Hematol. 2009 Apr;46(2):166-75. To Reference
Ref 3Akt enzyme: new therapeutic target in cancer and diabetes?. Orv Hetil. 2009 Feb 22;150(8):373-8. To Reference


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