Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000273

Drug Information
SynonymsLonapalenum; CHEBI:153018; Lonapaleno [Spanish]; CHEMBL36648; Lonapalene (USAN); RS-43179; CID56237; Lonapalenum [Latin]; LONAPALENE; RS 43179; D04770; 6-Chloro-2,3-dimethoxy-1,4-naphthalenediol diacetate; AC1L1KN9; Lonapaleno; (4-acetyloxy-6-chloro-2,3-dimethoxynaphthalen-1-yl) acetate; 91431-42-4
CompanyBristol-Myers Squibb
[ICD9: 696   ICD10: L40]
Discotinued in Phase III    

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
Canonical SMILESCC(=O)OC1=C(C(=C(C2=C1C=CC(=C2)Cl)OC(=O)C)OC)OC    
CAS NumberCAS 91431-42-4
PubChem Compound IDCID 56237.
PubChem Substance IDSID 193575.
TargetArachidonate 5-lipoxygenaseInhibitor[1][2]
Ref 1Preview of potential therapeutic applications of leukotriene B4 inhibitors in dermatology. Skin Pharmacol Appl Skin Physiol. 2000 Sep-Oct;13(5):235-45. To Reference
Ref 2Pharmacologic and clinical effects of lonapalene (RS 43179), a 5-lipoxygenase inhibitor, in psoriasis. J Invest Dermatol. 1990 Jul;95(1):50-4. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543