Therapeutic Targets Database
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TTD Drug ID: DCL000292

Drug Information
NameSU5614
SynonymsMolPort-006-389-303; su5614; SU-5614; CID6536806; (3Z)-5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one; C416849; 5-Chloro-3-[(3,5-dimethylpyrrol-2-yl)methylene]-2-indolinone; SU 5614; AC1O6W2Q
CompanySugen Pharmaceuticals
IndicationAirway inflammation
[ICD9: 460-519   ICD10: J00-J99]
Phase I/II    
Structure

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InChI1S/C15H13ClN2O/c1-8-5-9(2)17-14(8)7-12-11-6-10(16)3-4-13(11)18-15
(12)19/h3-7,17H,1-2H3,(H,18,19)/b12-7-
InChIKeyXLBQNZICMYZIQT-GHXNOFRVSA-N
Canonical SMILESCC1=CC(=C(N1)C=C2C3=C(C=CC(=C3)Cl)NC2=O)C    
Isomeric SMILESCC1=CC(=C(N1)/C=C\2/C3=C(C=CC(=C3)Cl)NC2=O)C
CAS NumberCAS 186611-56-3
PubChem Compound IDCID 6536806.
PubChem Substance IDSID 11643921.
TargetFL cytokine receptorInhibitor[1]
Ref 1FMS-like tyrosine kinase 3-internal tandem duplication tyrosine kinase inhibitors display a nonoverlapping profile of resistance mutations in vitro. Cancer Res. 2009 Apr 1;69(7):3032-41. Epub 2009 Mar 24. To Reference



 

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