Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000295

Drug Information
SynonymsAC1L3WN5; XR9576; Tariquidar; CID148201; N-(2-((4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)carbamoyl)-4,5-dimethoxyphenyl)quinoline-3-carboxamide; D06008; XR 9576; 3-Quinolinecarboxamide, N-(2-(((4-(2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl)phenyl)amino)carbonyl)-4,5-dimethoxyphenyl)-; 206873-63-4; tariquidarth; N-[2-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide; C402343; Tariquidar (USAN/INN); CHEBI:359664; UNII-J58862DTVD; CHEMBL348475
CompanyXenova Group Ltd.
IndicationAdrenocortical carcinoma
[ICD9: 194   ICD10: C74.0]
Phase II completed    

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Canonical SMILESCOC1=C(C=C2CN(CCC2=C1)CCC3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4NC(=O)C5=CC6=CC=
CAS NumberCAS 206873-63-4
PubChem Compound IDCID 148201.
PubChem Substance IDSID 725890.
TargetMultidrug resistance proteinModulator[1][2]
Ref 1Synthesis and biological evaluation of a small molecule library of 3rd generation multidrug resistance modulators. Bioorg Med Chem. 2009 Mar 15;17(6):2524-35. Epub 2009 Feb 5. To Reference
Ref 2Thiazolides: a new class of antiviral drugs. Expert Opin Drug Metab Toxicol. 2009 Jun;5(6):667-74. To Reference


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