Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DCL000335

Drug Information
NameAgomelatine
SynonymsS-20098; N-(2-(7-Methoxynaphth-1-yl)ethyl)acetamide; S 20098; AGO-178; ZINC00005608; C15H17NO2; D02578; Valdoxan; 138112-76-2; AGO178; N-(2-(7-methoxy-1-naphthyl)ethyl)acetamide; Thymanax; CID82148; AC-3395; S1243_Selleck; N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide; Valdoxan (TN); AKOS005145681; L000528; PDSP2_001767; PDSP1_001784; C084711; S20098; PDSP2_001289; AGO 178; Agomelatine [INN]; UNII-137R1N49AD; N-(2-(7-Methoxy-1-naphthalenyl)ethyl)acetamide; CHEBI:108209; AC1L32UM; PDSP1_001305; I14-1072; CHEMBL10878; Valdoxan, Melitor, Thymanax, Agomelatine; Agomelatine (INN); LS-9830; Agomelatine; Acetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-
CompanyServier
IndicationMajor depressive disorder
[ICD9: 296.2, 296.3   ICD10: F32, F33]
Withdrawn in MAA    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/
h3-7,10H,8-9H2,1-2H3,(H,16,17)
InChIKeyYJYPHIXNFHFHND-UHFFFAOYSA-N
Canonical SMILESCC(=O)NCCC1=CC=CC2=C1C=C(C=C2)OC    
CAS NumberCAS 138112-76-2
PubChem Compound IDCID 82148.
PubChem Substance IDSID 659078.
SuperDrug ATC IDN06AX22
N06AX22
ClinicalTrials.govNCT00463242;
TargetMelatonin receptor type 1AAgonist[2]
Ref 1Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology. 2008 Aug;33(9):2080-92. Epub 2008 Jan 2. To Reference
Ref 2Curr Top Med Chem. 2008;8(11):954-68.Melatonin receptor agonists: SAR and applications to the treatment of sleep-wake disorders. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543