Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000342

Drug Information
CompanyPfizer / Sugen
IndicationAdvanced solid tumours
[ICD9: 140-199   ICD10: C00-C75, C7A, C7B]

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Canonical SMILESCC1=C(NC(=C1CCC(=O)O)C)C=C2C3=CC=CC=C3NC2=O    
Isomeric SMILESCC1=C(NC(=C1CCC(=O)O)C)/C=C\2/C3=CC=CC=C3NC2=O
Therapeutic ClassAntineoplastic Agents
PubChem Compound IDCID 5329099.
TargetAurora AInhibitor[1][2]
Aurora AMultitarget[1][2]
Aurora BInhibitor[1][2]
Aurora BMultitarget[1][2]
Basic fibroblast growth factor receptor 1 Inhibitor[1][2]
Basic fibroblast growth factor receptor 1 Multitarget[1][2]
Platelet-derived growth factor receptorInhibitor[1][2]
Platelet-derived growth factor receptorMultitarget[1][2]
Vascular endothelial growth factor receptor 2Inhibitor[1][2]
Vascular endothelial growth factor receptor 2Multitarget[1][2]
Ref 1A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development. Curr Top Med Chem. 2007;7(14):1408-22. To Reference
Ref 2Dose-finding study of the multitargeted tyrosine kinase inhibitor SU6668 in patients with advanced malignancies. Clin Cancer Res. 2005 Sep 1;11(17):6240-6. To Reference


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