Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000352

Drug Information
Synonyms3-(quinolin-4-ylmethylamino)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-carboxamide; 728033-96-3; OSI 930; S1220_Selleck; CID9868037; OSI930; OSI-930; OSI-930 is a multi-targeted tyrosine kinase inhibitor
CompanyOSI Pharmaceuticals
IndicationVarious cancers
[ICD9: 140-229   ICD10: C00-C96]
Phase I    

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Canonical SMILESC1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F    
Therapeutic ClassAntineoplastic Agents
PubChem Compound IDCID 9868037.
PubChem Substance IDSID 14832924.
TargetMast/stem cell growth factor receptorInhibitor[1]
Mast/stem cell growth factor receptorMultitarget[1]
Vascular endothelial growth factor receptor 2Inhibitor[1]
Vascular endothelial growth factor receptor 2Multitarget[1]
Ref 1A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development. Curr Top Med Chem. 2007;7(14):1408-22. To Reference


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