Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000361

Drug Information
SynonymsCID10297043; CHEMBL587723; AEE-788, NVP-AEE 788, AEE788; GNF-Pf-5343; CHEBI:40629; 497839-62-0; 1H-Pyrrolo(2,3-d)pyrimidin-4-amine, 6-(4-((4-ethyl-1-piperazinyl)methyl)phenyl)-N-((1R)-1-phenylethyl)-; CID 11578515; CID11578515; S1486_Selleck; AEE788; AEE; AEE 788
CompanyNovartis AG
IndicationSolid tumours
[ICD9: 140-199   ICD10: C00-C75, C7A, C7B]
Discontinued in Phase II    

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Canonical SMILESCCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4NC(C)C5=CC=CC=C5    
Therapeutic ClassAntineoplastic Agents
PubChem Compound IDCID 11578515.
PubChem Substance IDSID 10549896.
TargetFibroblast growth factor receptor 2Inhibitor[1]
Fibroblast growth factor receptor 2Multitarget[1]
Fibroblast growth factor receptor 3Inhibitor[1]
Fibroblast growth factor receptor 3Multitarget[1]
Ref 1A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development. Curr Top Med Chem. 2007;7(14):1408-22. To Reference


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