Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000365

Drug Information
SynonymsEC-000.2350; 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE; PD-332991; CHEMBL189963; S1116_Selleck; CID5330286; Pyrido(2,3-d)pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(1-piperazinyl)-2-pyridinyl)amino)-; LQQ; 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one; 2euf; Kinome_3823; 6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-ylpyridin-2-ylamino)-8H-pyrido(2,3-d)pyrimidin-7-one; PD0332991; 571190-30-2; PD 332991, PD 0332991, PD0332991; AC1NS8RV; Kinome_3824; PD-0332991; PD 0332991
CompanyOnyx Pharmaceuticals/Pfizer
IndicationVarious cancers
[ICD9: 140-229   ICD10: C00-C96]
Phase II    

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Canonical SMILESCC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C    
Therapeutic ClassAntineoplastic Agents
CAS NumberCAS 571190-30-2
PubChem Compound IDCID 5330286.
PubChem Substance IDSID 8035907.
TargetCell division protein kinase 4Inhibitor[1]
Ref 1A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development. Curr Top Med Chem. 2007;7(14):1408-22. To Reference


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