Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000366

Drug Information
NameRo 31-7453
SynonymsAC1NS2UU; CID5327686; Bisindolylmaleimide deriv. 44; Ro-31-7453; 3-(1-methylindol-3-yl)-4-(1-methyl-6-nitroindol-3-yl)pyrrole-2,5-dione; MKC-1; CHEMBL52885
CompanyHoffmann La Roche
IndicationOvarian Cancer; Endometrial Cancer
[ICD9: 140-229, 182.0, 183   ICD10: C00-C96, C54.1, C56]
Phase II    

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
Canonical SMILESCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=C4C=CC(=C5)[N+](=O)[O-])C    
Therapeutic ClassAntineoplastic Agents
CAS NumberCAS 443912-18-3
PubChem Compound IDCID 5327686.
PubChem Substance IDSID 8032392.
TargetCell division protein kinase 1Inhibitor[1]
Cell division protein kinase 1Multitarget[1]
Cell division protein kinase 2Inhibitor[1]
Cell division protein kinase 2Multitarget[1]
Cell division protein kinase 4Inhibitor[1]
Cell division protein kinase 4Multitarget[1]
Ref 1A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development. Curr Top Med Chem. 2007;7(14):1408-22. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543