Therapeutic Targets Database
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TTD Drug ID: DCL000571

Drug Information
NameMK-4827
SynonymsMK-4827; CHEBI:724225; CHEMBL1094636
CompanyMerck
IndicationCancer; Solid Tumors
[ICD9: 140-199, 140-229, 210-229   ICD10: C00-C75, C00-C96, C7A, C7B, D10-D36, D3A]
Phase I    
Structure

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InChI1S/C19H20N4O.ClH/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-1
3(7-9-16)14-4-2-10-21-11-14;/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,2
0,24);1H/t14-;/m1./s1
InChIKeyYXYDNYFWAFBCAN-PFEQFJNWSA-N
Canonical SMILESC1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N.Cl    
Isomeric SMILESC1C[C@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N.Cl
PubChem Compound IDCID 44550597.
PubChem Substance IDSID 87233600.
ClinicalTrials.govNCT01110603;
TargetPoly [ADP-ribose] polymerase 1Inhibitor[1][2]
Ref 1Merck. Product Development Pipeline. July 15 2009. To Reference
Ref 2Merck. Report of Merck. April 2009. To Reference



 

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