Therapeutic Targets Database
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TTD Drug ID: DCL000633

Drug Information
NameRosiglitazone XR
SynonymsSAM001246610; CPD000471612; HMS2051B11; AC1NQXYB; MLS001401426; MolPort-003-850-205; UNII-KX2339DP44; CID5281055; Nyracta; CHEBI:162701; NSC717764; 2,4-Thiazolidinedione,5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-,(2Z)-2-butenedioate; MLS001306472; Rosiglitazone Maleate [USAN]; Avandia; AC-737; Rosiglitazone XR; S2505_Selleck; CHEMBL843; SB-206846; (+-)-5-(p-(2-(Methyl-2-pyridylamino)ethoxy)benzyl)-2,4-thiazolidinedione maleate (1:1); (Z)-but-2-enedioic acid; 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione; Avandia (TN); BRL 49653-C; Rosiglitazone maleate (JAN/USAN); 5-{[4-({2-[methyl(pyridin-2-yl)amino]ethyl}oxy)phenyl]methyl}-1,3-thiazolidine-2,4-dione (2Z)-but-2-enedioate; BRL-49653C; BRL 49653C; BB_SC-4138; CHEBI:8892; C18H19N3O3S.C4H4O4; Venvia; D00596; Avandia administration for 6-12 weeks; 155141-29-0; SMR000471612; SB-210232; (+ -)-5-[[4-2-(methyl]-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione,(Z)-2-butenedioate (1:1); 2,4-Thiazolidinedione, 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-, (2Z)-2-butenedioate (1:1); Rosiglitazone maleate; 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino) ethoxy]phenyl]methyl]-, (2Z)-2-butenedioate (1:1)
CompanyGSK
IndicationAlzheimer's disease
[ICD9: 331.0   ICD10: G30]
Phase III    
Structure

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InChI1S/C18H19N3O3S.C4H4O4/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6
-8-14)12-15-17(22)20-18(23)25-15;5-3(6)1-2-4(7)8/h2-9,15H,10-12H2
,1H3,(H,20,22,23);1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKeySUFUKZSWUHZXAV-BTJKTKAUSA-N
Canonical SMILESCN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=CC(=O)O)C(=O)O    
Isomeric SMILESCN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=C\C(=O)O)\C(=O)O
CAS NumberCAS 122320-73-4
FormulaC22H23N3O7S
PubChem Compound IDCID 5281055.
PubChem Substance IDSID 534302.
SuperDrug ATC IDA10BG02
SuperDrug CAS ID122320734;
ClinicalTrials.govNCT00428090;
TargetPPAR gammaAgonist[1]
Ref 1GSK. Product Development Pipeline. February 2009. To Reference



 

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