Therapeutic Targets Database
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TTD Drug ID: DCL000771

Drug Information
NameDexefaroxan
SynonymsDexefaroxan; 2-Imidazoline, 2-(2-ethyl-2,3-dihydro-2-benzofuranyl)-, ( )-(R)-; NCGC00015410-01; KST-1A1946; AR-1A0132; Lopac-E-3263; CID208820; UNII-F751MO69EV; AC1Q4UEV; AC1L4LF7; (+)-(r)-2-(2-ethyl-2,3-dihydro-2-benzofuranyl)-2-imidazoline; NCGC00024793-01; Tocris-0792; 2-[(2R)-2-ethyl-3H-1-benzofuran-2-yl]-4,5-dihydro-1H-imidazole; Dexefaroxan [INN]; 16950-79-1
CompanyPierre Fabre
IndicationSchizophrenia
[ICD9: 295   ICD10: F20]
Discontinued in Phase II    [1]
Structure

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InChI1S/C13H16N2O/c1-2-13(12-14-7-8-15-12)9-10-5-3-4-6-11(10)16-13/h3-
6H,2,7-9H2,1H3,(H,14,15)/t13-/m1/s1
InChIKeyRATZLMXRALDSJW-CYBMUJFWSA-N
Canonical SMILESCCC1(CC2=CC=CC=C2O1)C3=NCCN3    
Isomeric SMILESCC[C@@]1(CC2=CC=CC=C2O1)C3=NCCN3
CAS NumberCAS 143249-88-1
PubChem Compound IDCID 208820.
PubChem Substance IDSID 783638.
TargetAdenosine receptor A2aAgonist[1]
Adenosine receptor A2aMultitarget[1]
Nicotinic acetylcholine receptorAgonist[1]
Nicotinic acetylcholine receptorMultitarget[1]
Ref 1The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31. To Reference



 

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