Therapeutic Targets Database
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TTD Drug ID: DCL000918

Drug Information
NamePD-158771
Synonyms2-Pyrimidinamine, N-(4-(2-(4-phenyl-1-piperazinyl)ethyl)cyclohexyl)-, trans-; 189152-50-9; CHEMBL165679; CHEBI:374449; LS-134503; CID3075615; CHEBI:375533; trans-N-(4-(2-(4-Phenyl-1-piperazinyl)ethyl)cyclohexyl)-2-pyrimidinamine; PD 158771; L015054; N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine; AC1MIP35; CHEMBL164984
CompanyPfizer
IndicationSchizophrenia
[ICD9: 295   ICD10: F20]
Preclinical    [1]
Structure

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InChI1S/C22H31N5/c1-2-5-21(6-3-1)27-17-15-26(16-18-27)14-11-19-7-9-20(
10-8-19)25-22-23-12-4-13-24-22/h1-6,12-13,19-20H,7-11,14-18H2,(H,
23,24,25)
InChIKeyOUUMPVSFLSOGJZ-UHFFFAOYSA-N
Canonical SMILESC1CC(CCC1CCN2CCN(CC2)C3=CC=CC=C3)NC4=NC=CC=N4    
FormulaC22H31N5
PubChem Compound IDCID 3075615.
PubChem Substance IDSID 3877216.
Target5-hydroxytryptamine receptor 1A Antagonist[1]
5-hydroxytryptamine receptor 1A Multitarget[1]
D(2) dopamine receptorAntagonist[1]
D(2) dopamine receptorMultitarget[1]
D(3) dopamine receptorAntagonist[1]
D(3) dopamine receptorMultitarget[1]
Ref 1The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31. To Reference



 

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