Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DCL000932

Drug Information
NamePirfenidone
Synonyms5-21-07-00197 (Beilstein Handbook Reference); Lopac0_000907; BRD-K96862998-001-03-1; I01-1466; BRN 1526549; Esbriet; Pirfenidonum [INN-Latin]; Pirfenidona; 5-methyl-1-phenylpyridin-2-one; S-7701; Lopac-P-2116; Bio1_001375; 5-Methyl-1-phenyl-2-(1H)-pyridone; 2(1H)-Pyridinone, 5-methyl-1-phenyl-; C093844; NCGC00015806-05; SMR000326900; AMR-69; 53179-13-8; 5-Methyl-1-phenyl-2(1H)-pyridone; LS-133834; 5-methyl-1-phenylpyridin-2(1H)-one; ZINC00001958; NCGC00024992-02; MLS000860042; PIRFENIDONE; Deskar; 5-Methyl-1-phenyl-1H-pyridin-2-one; CID40632; AC1L2454; NCGC00015806-03; Bio1_000886; EN000704; EU-0100907; FT-0082541; AC-6797; Pirfenidonum; Pirfenidone (JAN/USAN/INN); KS-5041; P 2116; Pirespa; Pirfenidone [USAN:INN]; AMR 69; NCGC00024992-01; Tocris-1093; Pirfenidona [INN-Spanish]; D01583; F-647; NCGC00024992-03; C12H11NO; Bio1_000397; P2116_SIGMA; Pirfenidone (Deskar); 2(1H)-Pyridone, 5-methyl-1-phenyl-; NCGC00015806-01
CompanyInterMune
IndicationIdiopathic pulmonary fibrosis
[ICD9: 516.3   ICD10: J84.1]
Discontinued in Phase III    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
InChIKeyISWRGOKTTBVCFA-UHFFFAOYSA-N
Canonical SMILESCC1=CN(C(=O)C=C1)C2=CC=CC=C2    
CAS NumberCAS 53179-13-8
PubChem Compound IDCID 40632.
PubChem Substance IDSID 181472.
SuperDrug ATC IDL04AX05
ClinicalTrials.govNCT00287716;
TargetTGF-betaInhibitor[2]
TGF-betaMultitarget[2]
TNF alphaInhibitor[2]
TNF alphaMultitarget[2]
Ref 1Agents in development for the treatment of diabetic nephropathy. Expert Opin Emerg Drugs. 2008 Sep;13(3):447-63. To Reference
Ref 2Current and emerging drugs for idiopathic pulmonary fibrosis. Expert Opin Emerg Drugs. 2007 Nov;12(4):627-46. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543