Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DCL000973

Drug Information
NameSarizotan
SynonymsAC1MHW5N; 1-(3,4-dihydro-2H-chromen-2-yl)-N-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]methanamine; CID3058747; L001578; UNII-467LU0UCUW; Sarizotan; N-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-5-(4-fluorophenyl)-3-pyridinemethanamine; EMD 128130; 177975-08-5; (-)-3-((((R)-2-Chromanylmethyl)amino)methyl)-5-(p-fluorophenyl)pyridine; Sarizotan [INN]; LS-192590
CompanyEMD Serono
IndicationParkinsoní»s Disease
[ICD9: 332   ICD10: F02.3, G20]
Discontinued in Phase II    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C22H21FN2O/c23-20-8-5-17(6-9-20)19-11-16(12-24-14-19)13-25-15-
21-10-7-18-3-1-2-4-22(18)26-21/h1-6,8-9,11-12,14,21,25H,7,10,13,1
5H2
InChIKeyHKFMQJUJWSFOLY-UHFFFAOYSA-N
Canonical SMILESC1CC2=CC=CC=C2OC1CNCC3=CN=CC(=C3)C4=CC=C(C=C4)F    
CAS NumberCAS 177976-12-4
FormulaC22H21FN2O
PubChem Compound IDCID 3058747.
PubChem Substance IDSID 3862729.
ClinicalTrials.govNCT00314288;
Target5-hydroxytryptamine receptor 1AAgonist[1]
5-hydroxytryptamine receptor 1AMultitarget[1]
D(3) dopamine receptorAgonist[1]
D(3) dopamine receptorMultitarget[1]
D(4) dopamine receptorAgonist[1]
D(4) dopamine receptorMultitarget[1]
Ref 1Drugs used to treat Parkinson's disease, present status and future directions. CNS Neurol Disord Drug Targets. 2008 Oct;7(4):321-42. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543