Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL001022

Drug Information
SynonymsTraxoprodil; 1-Piperidineethanol, 4-hydroxy-alpha-(4-hydroxyphenyl)-beta-methyl-4-phenyl-, (alphaS,betaS)-; CID219101; 15571-11-6; ( )-CP 101606; LS-184042; 1-Piperidineethanol, 4-hydroxy-alpha-(4-hydroxyphenyl)-beta-methyl-4-phenyl-, (S-(R*,R*))-; AC1L5621; CP101606; CP-101606; AC1Q59EY; CHEMBL17350; CP 98113; CHEBI:119774; Traxoprodil [INN]; CP 101,606; AR-1B8535; CP 101606; 1-[(1s,2s)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]-4-phenylpiperidin-4-ol; KST-1B0691
IndicationParkinson's DiseaseDiscontinued in Phase I    [1]
Severe Mood Disorders
[ICD9: 296   ICD10: F30-F39]
Discontinued in Phase II    [1]

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
Canonical SMILESCC(C(C1=CC=C(C=C1)O)O)N2CCC(CC2)(C3=CC=CC=C3)O    
Isomeric SMILESC[C@@H]([C@H](C1=CC=C(C=C1)O)O)N2CCC(CC2)(C3=CC=CC=C3)O
Therapeutic ClassAnalgesics
CAS NumberCAS 189894-57-3
PubChem Compound IDCID 219101.
PubChem Substance IDSID 791640.
TargetNMDA receptorsubunit epsilon-2 Antagonist[2]
NMDA receptorsubunit epsilon-2 Antagonist[1][2]
Ref 1Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology. 2008 Aug;33(9):2080-92. Epub 2008 Jan 2. To Reference
Ref 2Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol. 2006 Feb;6(1):7-17. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543