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TTD Drug ID:
DCL001072
Drug
Information |
Name | GSK1070916 | Synonyms | CHEBI:722556; AKOS005145558; CHEMBL1090479; GSK-1070916 | Company | GlaxoSmith-Kline | Indication | Advanced solid tumours [ICD9: 140-199 ICD10: C00-C75, C7A, C7B] | Phase I | Structure |
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| InChI | 1S/C30H33N7O/c1-6-37-19-26(28(34-37)21-10-12-23(13-11-21)32-30(38 )36(4)5)24-14-15-31-29-25(24)17-27(33-29)22-9-7-8-20(16-22)18-35( 2)3/h7-17,19H,6,18H2,1-5H3,(H,31,33)(H,32,38) | InChIKey | QTBWCSQGBMPECM-UHFFFAOYSA-N | Canonical SMILES | CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5) CN(C)C | PubChem Compound ID | CID 46885626. | PubChem Substance ID | SID 103748127. | Target | Aurora B |  | Inhibitor | [1] | Aurora B |  | Multitarget | [1] | Aurora C |  | Inhibitor | [1] | Aurora C |  | Multitarget | [1] | Ref 1 | Nat Rev Drug Discov. 2009 Jul;8(7):547-66.Cell cycle kinases as therapeutic targets for cancer. To Reference |
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