TTD Drug ID: DCL001072

Drug Information
Name	GSK1070916
Synonyms	CHEBI:722556; AKOS005145558; CHEMBL1090479; GSK-1070916
Company	GlaxoSmith-Kline
Indication	Advanced solid tumours [ICD9: 140-199   ICD10: C00-C75, C7A, C7B]			Phase I
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C30H33N7O/c1-6-37-19-26(28(34-37)21-10-12-23(13-11-21)32-30(38 )36(4)5)24-14-15-31-29-25(24)17-27(33-29)22-9-7-8-20(16-22)18-35( 2)3/h7-17,19H,6,18H2,1-5H3,(H,31,33)(H,32,38)
InChIKey	QTBWCSQGBMPECM-UHFFFAOYSA-N
Canonical SMILES	CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5) CN(C)C
PubChem Compound ID	CID 46885626.
PubChem Substance ID	SID 103748127.
Target	Aurora B			Inhibitor	[1]
	Aurora B			Multitarget	[1]
	Aurora C			Inhibitor	[1]
	Aurora C			Multitarget	[1]
Ref 1	Nat Rev Drug Discov. 2009 Jul;8(7):547-66.Cell cycle kinases as therapeutic targets for cancer. To Reference

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