Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DCL001076

Drug Information
NamePF-03814735
CompanyPfizer
IndicationAdvanced solid tumours
[ICD9: 140-199   ICD10: C00-C75, C7A, C7B]
Phase I    
Structure

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InChI1S/C23H25F3N6O2/c1-12(33)27-11-20(34)32-18-7-8-19(32)16-9-14(5-6-
15(16)18)30-22-28-10-17(23(24,25)26)21(31-22)29-13-3-2-4-13/h5-6,
9-10,13,18-19H,2-4,7-8,11H2,1H3,(H,27,33)(H2,28,29,30,31)
InChIKeyRYYNGWLOYLRZLK-UHFFFAOYSA-N
Canonical SMILESCC(=O)NCC(=O)N1C2CCC1C3=C2C=CC(=C3)NC4=NC=C(C(=N4)NC5CCC5)C(F)(F)F    
PubChem Compound IDCID 49830590.
ClinicalTrials.govNCT00424632;
TargetAurora AInhibitor[1]
Aurora AMultitarget[1]
Aurora BInhibitor[1]
Aurora BMultitarget[1]
Ref 1Nat Rev Drug Discov. 2009 Jul;8(7):547-66.Cell cycle kinases as therapeutic targets for cancer. To Reference



 

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