Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL001088

Drug Information
SynonymsGD9; 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine; EC-000.2335; 4-(2-(1H-Indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine; GDC-0941, GDC0941; GDC-0941; nchembio.293-comp12; C53216200; Kinome_3719; GDC 0941; GDC0941; CHEMBL521851; S1065_Selleck
IndicationAdvanced solid tumours; non-Hodgkin¡¯s lymphoma
[ICD9: 140-199, 200, 202, 202.8, 210-229   ICD10: C00-C75, C7A, C7B, C81-C96, C82-C85, D10-D36, D3A]
Phase I    

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Canonical SMILESCS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6    
PubChem Compound IDCID 17755052.
PubChem Substance IDSID 29212926.
Ref 1Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov. 2009 Aug;8(8):627-44. To Reference
Ref 2The PI3K/Akt pathway as a target in the treatment of hematologic malignancies. Anticancer Agents Med Chem. 2009 Jun;9(5):550-9. To Reference


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