Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNAP001678

Drug Information
NamePonatinib
Trade NameIclusig
CompanyARIAD Pharmaceuticals Cambridge, MA
IndicationAML
[ICD9: 205.0   ICD10: C92.0]
Phase I    
Chronic, accelerated or blast-phase chronic myeloid leukaemia
[ICD9: 208.9   ICD10: C91-C95]
Approved    
Newly-diagnosed CML
[ICD9: 205.1   ICD10: C92.1]
Phase III    
Philadelphia-positive ALL, CML
[ICD9: 204.0, 205.1   ICD10: C91.0, C92.1]
Phase II    
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C29H27F3N6O.ClH/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-
34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-3
6(2)13-15-37;/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39);1H
InChIKeyBWTNNZPNKQIADY-UHFFFAOYSA-N
Canonical SMILESCC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=
CC=C5.Cl    
CAS NumberCAS 943319-70-8
FormulaC29H28ClF3N6O
PubChem Compound IDCID 46908927.
SuperDrug ATC IDL01XE24
TargetAbl
FLT3
KIT
RET



 

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