Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC000124

Drug Information
NameA-381393
IndicationNot AvailableExperimental    
Structure

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InChI1S/C20H24N4/c1-15-7-8-17(13-16(15)2)24-11-9-23(10-12-24)14-20-21-
18-5-3-4-6-19(18)22-20/h3-8,13H,9-12,14H2,1-2H3,(H,21,22)
InChIKeySAQMCVDGOIRQTC-UHFFFAOYSA-N
Canonical SMILESCC1=C(C=C(C=C1)N2CCN(CC2)CC3=NC4=CC=CC=C4N3)C    
PubChem Compound IDCID 11301655.
TargetD(4) dopamine receptorAntagonist[1][2]
Ref 1Dopamine D4 receptor involvement in the discriminative stimulus effects in rats of LSD, but not the phenethylamine hallucinogen DOI. Psychopharmacology (Berl). 2009 Apr;203(2):265-77. Epub 2008 Jul 6. To Reference
Ref 2Comparative molecular field analysis of dopamine D4 receptor antagonists including 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 113), 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]-1H-pyrrolo-[2,3-b]pyridine (L-745,870), and clozapine. J Med Chem. 2001 Apr 12;44(8):1151-7. To Reference



 

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