Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC000130

Drug Information
IndicationNot AvailableExperimental    

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Canonical SMILESCC1=NOC(=C1)C2CCCN2C    
Isomeric SMILESCC1=NOC(=C1)[C@@H]2CCCN2C
CAS NumberCAS 147402-53-7
PubChem Compound IDCID 119380.
PubChem Substance IDSID 696060.
TargetNeuronal acetylcholine receptor protein, alpha-4 chainAgonist[1]
Neuronal acetylcholine receptor protein, beta-2 chainAgonist[2][1]
Nicotinic acetylcholine receptorAgonist[3]
Ref 1(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization. J Pharmacol Exp Ther. 1994 Jul;270(1):319-28. To Reference
Ref 2Nicotine, brain nicotinic receptors, and neuropsychiatric disorders. Arch Med Res. 2000 Mar-Apr;31(2):131-44. To Reference
Ref 3Enhancement of sustained attention performance by the nicotinic acetylcholine receptor agonist ABT-418 in intact but not basal forebrain-lesioned rats. Psychopharmacology (Berl). 1999 May;144(2):175-82. To Reference


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