Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC000133

Drug Information
NameABT-594
IndicationNot AvailableExperimental    
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C9H11ClN2O/c10-9-2-1-8(5-12-9)13-6-7-3-4-11-7/h1-2,5,7,11H,3-4
,6H2/t7-/m1/s1
InChIKeyMKTAGSRKQIGEBH-SSDOTTSWSA-N
Canonical SMILESC1CNC1COC2=CN=C(C=C2)Cl    
Isomeric SMILESC1CN[C@H]1COC2=CN=C(C=C2)Cl
CAS NumberCAS 198283-73-7
PubChem Compound IDCID 3075702.
PubChem Substance IDSID 3877294.
TargetNeuronal acetylcholine receptor protein, alpha-4 chainAgonist[1]
Neuronal acetylcholine receptor protein, beta-2 chainAgonist[1]
Nicotinic acetylcholine receptorAgonist[2][1]
Ref 1The nicotinic acetylcholine receptor agonist ABT-594 increases FGF-2 expression in various rat brain regions. Neuroreport. 1999 Dec 16;10(18):3909-13. To Reference
Ref 2ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective antinociceptive agent acting via neuronal nicotinic acetylcholine receptors: II. In vivo characterization. J Pharmacol Exp Ther. 1998 May;285(2):787-94. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543