Therapeutic Targets Database
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TTD Drug ID: DNC000317

Drug Information
NameBIBP 3226
IndicationNot AvailableExperimental    
Structure

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InChI1S/C27H31N5O3/c28-27(29)30-17-7-12-23(25(34)31-18-19-13-15-22(33)
16-14-19)32-26(35)24(20-8-3-1-4-9-20)21-10-5-2-6-11-21/h1-6,8-11,
13-16,23-24,33H,7,12,17-18H2,(H,31,34)(H,32,35)(H4,28,29,30)/t23-
/m1/s1
InChIKeyKUWBXRGRMQZCSS-HSZRJFAPSA-N
Canonical SMILESC1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NCC3=CC=C(C=C3)O    
Isomeric SMILESC1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)N[C@H](CCCN=C(N)N)C(=O)NCC3=CC=C(C=C3)O
PubChem Compound IDCID 5311023.
PubChem Substance IDSID 7978787.
TargetNeuropeptide Y receptor type 1Antagonist[1][2]
Ref 1Effects of a selective neuropeptide Y Y(1) receptor antagonist BIBP 3226 on double peaked vasoconstrictor responses to periarterial nerve stimulation in canine splenic arteries. Br J Pharmacol. 2000 Aug;130(7):1699-705. To Reference
Ref 2Intracerebroventricular injection of a neuropeptide Y-Y1 receptor agonist increases while BIBP3226, a Y1 antagonist, reduces the infarct volume following transient middle cerebral artery occlusion in rats. Neuroscience. 2003;116(1):119-26. To Reference



 

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