Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC000392

Drug Information
NameCBR-2092
CompanyCumbre
IndicationBacterial infections
[ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104   ICD10: A00-A09, A15-A19, A20-A28, A30-A49, A65-A69, A70-A74, A75-A79]
Experimental    
Structure

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InChI1S/C65H81FN6O15/c1-31-13-12-14-32(2)61(80)68-50-44(56(77)47-48(57
(50)78)55(76)37(7)59-49(47)60(79)64(9,87-59)85-26-20-46(84-11)33(
3)58(86-38(8)73)36(6)54(75)35(5)53(31)74)28-67-71-24-18-41(19-25-
71)69(10)65(21-22-65)40-17-23-70(29-40)52-34(4)51-42(39-15-16-39)
27-43(63(82)83)62(81)72(51)30-45(52)66/h12-14,20,26-28,30-31,33,3
5-36,39-41,46,53-54,58,67,74-76,78H,15-19,21-25,29H2,1-11H3,(H,68
,80)(H,82,83)/b13-12+,26-20+,32-14-,44-28+/t31-,33+,35+,36+,40+,4
6-,53-,54+,58+,64-/m0/s1
InChIKeyDTNAAUITOULVOL-NCMHXJFVSA-N
Canonical SMILESCC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCC(CC5)N(C)C6(CC6)C7CCN
(C7)C8=C(C9=C(C=C(C(=O)N9C=C8F)C(=O)O)C2CC2)C)C(=O)C(O4)(OC=CC(C(C(C(C(C
(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C    
Isomeric SMILESC[C@H]1/C=C/C=C(\C(=O)NC\2=C(C3=C(C(=C4C(=C3C(=O)/C2=C/NN5CCC(CC5)N(C)C6
(CC6)[C@@H]7CCN(C7)C8=C(C9=C(C=C(C(=O)N9C=C8F)C(=O)O)C2CC2)C)C(=O)[C@]
(O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)
C)C)OC)C)C)O)O)/C
PubChem Compound IDCID 44201351.
PubChem Substance IDSID 85197661.
TargetDNA topoisomerase 2-alphaBinder[1]
DNA topoisomerase 4 subunit ABinder[1]
DNA-dependent RNA polymeraseBinder[1]
Ref 1How many modes of action should an antibiotic have? Curr Opin Pharmacol. 2008 Oct;8(5):564-73. Epub 2008 Jul 30. To Reference



 

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