Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC000700

Drug Information
IndicationNot AvailableExperimental    

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Canonical SMILESCN1C2=CC=CC=C2C3=C4C(=C5C6=CC=CC=C6N(C5=C31)CCC#N)CNC4=O    
CAS NumberCAS 56-17-7
PubChem Compound IDCID 3501.
PubChem Substance IDSID 618246.
TargetNuclear factor NF-kappa-BInhibitor[1]
Protein kinase CInhibitor[2]
Protein kinase C, zeta typeInhibitor[3]
Ref 1Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8542-7. To Reference
Ref 2The protein kinase C inhibitor G?6976 is a potent inhibitor of DNA damage-induced S and G2 cell cycle checkpoints. Cancer Res. 2003 Jan 1;63(1):31-5. To Reference
Ref 3Protein kinase C zeta isoform is critical for proliferation in human glioblastoma cell lines. J Neurooncol. 2000 Apr;47(2):109-15. To Reference


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