Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC000777

Drug Information
NameICRF-193
IndicationNot AvailableExperimental    
Structure

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InChI1S/C12H18N4O4/c1-7(15-3-9(17)13-10(18)4-15)8(2)16-5-11(19)14-12(2
0)6-16/h7-8H,3-6H2,1-2H3,(H,13,17,18)(H,14,19,20)/t7-,8+
InChIKeyOBYGAPWKTPDTAS-OCAPTIKFSA-N
Canonical SMILESCC(C(C)N1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2    
Isomeric SMILESC[C@H]([C@H](C)N1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2
CAS NumberCAS 21416-88-6
PubChem Compound IDCID 119081.
PubChem Substance IDSID 695738.
TargetDNA topoisomerase IIInhibitor[1]
Ref 1The catalytic DNA topoisomerase II inhibitor ICRF-193 and all-trans retinoic acid cooperatively induce granulocytic differentiation of acute promyelocytic leukemia cells: candidate drugs for chemo-differentiation therapy against acute promyelocytic leukemia. Exp Hematol. 2002 Nov;30(11):1273-82. To Reference



 

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