Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC000938

Drug Information
NameMethylglyoxal (bis) guanylhydrazone
IndicationNot AvailableExperimental    

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Canonical SMILESCOC(=O)C1C(CCC2C1CC3C4=C(CCN3C2)C5=CC=CC=C5N4)O    
Isomeric SMILESCOC(=O)[C@@H]1[C@H](CC[C@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O
CAS NumberCAS 131-03-3
PubChem Compound IDCID 643606.
TargetS-adenosylmethionine decarboxylase proenzymeInhibitor[1][2]
Ref 1A phase I study of a new polyamine biosynthesis inhibitor, SAM486A, in cancer patients with solid tumours. Br J Cancer. 2000 Sep;83(5):594-601. To Reference
Ref 2CGP 48664, a potent and specific S-adenosylmethionine decarboxylase inhibitor: effects on regulation and stability of the enzyme. Biochem J. 1997 Feb 15;322 ( Pt 1):297-302. To Reference


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