Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC001189

Drug Information
NameR121919
IndicationDepression
[ICD9: 311   ICD10: F32]
Experimental    
Not AvailableExperimental    
Structure

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InChI1S/C22H32N6/c1-8-10-27(11-9-2)20-13-16(4)24-22-21(17(5)25-28(20)2
2)18-14-23-19(26(6)7)12-15(18)3/h12-14H,8-11H2,1-7H3/p+1
InChIKeyANNRUWYFVIGKHA-UHFFFAOYSA-O
Canonical SMILESCCCN(CCC)C1=[N+]2C(=NC(=C1)C)C(=C(N2)C)C3=CN=C(C=C3C)N(C)C    
CAS NumberCAS 195055-03-9
PubChem Compound IDCID 44400634.
PubChem Substance IDSID 53786946.
TargetCorticotropin releasing factor receptor 1Antagonist[1]
Corticotropin-releasing factor receptor 1 Antagonist[2]
Ref 1The CRH1 receptor antagonist R121919 attenuates stress-elicited sleep disturbances in rats, particularly in those with high innate anxiety. J Psychiatr Res. 2002 Jul-Aug;36(4):197-208. To Reference
Ref 2A review of drug options in age-related macular degeneration therapy and potential new agents. Expert Opin Pharmacother. 2006 Dec;7(17):2355-68. To Reference



 

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