| Drug
Information |
| Name | Ritanserin |
| Indication | Not Available | Experimental |
| Structure |
Click to save drug structure in 3D MOL format
Click to save drug structure in 2D MOL format
|
| InChI | 1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-1
3-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,
16-17H,10-15H2,1H3 |
| InChIKey | JUQLTPCYUFPYKE-UHFFFAOYSA-N |
| Canonical SMILES | CC1=C(C(=O)N2C=CSC2=N1)CCN3CCC(=C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)CC3 |
| CAS Number | CAS 87051-43-2 |
| PubChem Compound ID | CID 5074. |
| PubChem Substance ID | SID 193052. |
| Target | 5-hydroxytryptamine 2 receptor |  | Antagonist | [1][2][3][4] |
| 5-hydroxytryptamine 2A receptor | | Antagonist | [1][5][6] |
| 5-hydroxytryptamine 2B receptor | | Antagonist | [6] |
| 5-hydroxytryptamine 2C receptor | | Antagonist | [1][2][3][4] |
| 5-hydroxytryptamine receptor | | Antagonist | [4] |
| Ref 1 | Characterization of contractile 5-hydroxytryptamine receptor subtypes in the in situ autoperfused kidney in the anaesthetized rat. Eur J Pharmacol. 2008 Sep 11;592(1-3):133-7. Epub 2008 Jul 4. To Reference |
| Ref 2 | Hypersensitivity of 5-HT2 receptors in OCD patients. An increased prolactin response after a challenge with meta-chlorophenylpiperazine and pre-treatment with ritanserin and placebo. J Psychiatr Res. 2008 Sep;42(11):894-901. Epub 2008 Jun 3. To Reference |
| Ref 3 | Effects of antipsychotics and reference monoaminergic ligands on marble burying behavior in mice. Behav Pharmacol. 2008 Mar;19(2):145-52. To Reference |
| Ref 4 | Combined treatment of portal hypertension with ritanserin and propranolol in conscious and unrestrained cirrhotic rats. Hepatology. 1992 May;15(5):878-82. To Reference |
| Ref 5 | Human embryonic stem cell-derived oligodendrocyte progenitor cells express the serotonin receptor and are susceptible to JC virus infection. J Virol. 2008 Sep;82(17):8896-9. Epub 2008 Jun 25. To Reference |
| Ref 6 | p-Chloroamphetamine, a serotonin-releasing drug, elicited in rats a hyperglycemia mediated by the 5-HT1A and 5-HT2B/2C receptors. Eur J Pharmacol. 1998 Oct 23;359(2-3):185-90. To Reference |
