Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC001245

Drug Information
NameRWJ-67657
IndicationPain
[ICD9: 338,780   ICD10: R52, G89]
Experimental    
Structure

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InChI1S/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23
)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,3
2H,5-6,9,19-20H2
InChIKeyQSUSKMBNZQHHPA-UHFFFAOYSA-N
Canonical SMILESC1=CC=C(C=C1)CCCN2C(=NC(=C2C3=CC=NC=C3)C4=CC=C(C=C4)F)C#CCCO    
Therapeutic ClassAnalgesics
CAS NumberCAS 215303-72-3
PubChem Compound IDCID 3008319.
PubChem Substance IDSID 3720130.
TargetProstaglandin G/H synthase 2Inhibitor[1]
Ref 1Monocyte intracellular cytokine production during human endotoxaemia with or without a second in vitro LPS challenge: effect of RWJ-67657, a p38 MAP-kinase inhibitor, on LPS-hyporesponsiveness. Clin Exp Immunol. 2002 Feb;127(2):337-43. To Reference



 

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