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TTD Drug ID:
DNC001327
Drug
Information |
Name | SIB-1553A | Indication | Not Available | Experimental | Structure |
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| InChI | 1S/C13H19NOS.ClH/c1-14-9-2-3-11(14)8-10-16-13-6-4-12(15)5-7-13;/h 4-7,11,15H,2-3,8-10H2,1H3;1H | InChIKey | RJSVKPQKXSMZMT-UHFFFAOYSA-N | Canonical SMILES | CN1CCCC1CCSC2=CC=C(C=C2)O.Cl | CAS Number | CAS 205887-54-3 | PubChem Compound ID | CID 9881989. | PubChem Substance ID | SID 14848493. | Target | Neuronal acetylcholine receptor protein, beta-4 chain |  | Agonist | [1] | Nicotinic acetylcholine receptor |  | Agonist | [2] | Ref 1 | SIB-1553A, (+/-)-4-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride, a subtype-selective ligand for nicotinic acetylcholine receptors with putative cognitive-enhancing properties: effects on working and reference memory performances in aged rodents and nonhuman primates. J Pharmacol Exp Ther. 2001 Oct;299(1):297-306. To Reference | Ref 2 | The potential of subtype-selective neuronal nicotinic acetylcholine receptor agonists as therapeutic agents. Life Sci. 1998;62(17-18):1601-6. To Reference |
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